Pure Phenacetin Powder: A Brief Overview

Author: Hou

May. 18, 2023




Tags: Health & Medical


Phenacetin powder, known for its pain-relieving properties, has a long history of use as an analgesic and antipyretic. This article aims to provide an overview of pure phenacetin powder, including its uses, potential benefits, safety considerations, and any associated risks or precautions.

What is Phenacetin Powder?:

Phenacetin is an odorless, white crystalline powder that belongs to the class of para-aminophenol derivatives. It was first introduced in the late 19th century and gained popularity as an effective pain reliever and fever reducer. Pure phenacetin powder is often used as a pharmaceutical intermediate and has served as a building block for the synthesis of other drugs. However, due to safety concerns and potential adverse effects, its use as an over-the-counter analgesic has been limited or prohibited in many countries.

Historical Uses and Benefits :

Phenacetin gained significant recognition for its analgesic and antipyretic properties. In the past, it was commonly used to alleviate mild to moderate pain, including headaches, menstrual cramps, and muscle aches. Additionally, phenacetin was employed to reduce fever, making it a valuable component in various cold and flu remedies. Its ability to provide temporary relief from discomfort made it a popular choice among individuals seeking relief from everyday ailments.


Safety Considerations and Risks :

While phenacetin was once widely used, its safety profile has been a subject of concern. Prolonged or excessive use of phenacetin has been associated with potential health risks, particularly its link to renal (kidney) and hematological (blood-related) complications. In some cases, phenacetin use has been associated with a condition called analgesic nephropathy, which involves kidney damage and can lead to renal failure.

Due to these safety concerns, many countries have restricted or banned the use of phenacetin as an over-the-counter medication. It is important to note that the risks associated with phenacetin are primarily related to long-term, high-dose use.

Precautions and Regulation :

Given the potential risks associated with phenacetin, it is crucial to exercise caution when considering its use. It is recommended to consult a healthcare professional before using phenacetin or any analgesic medication. In countries where phenacetin is still available, it is important to strictly adhere to the recommended dosage and duration of use. Additionally, individuals with a history of kidney disease or blood disorders should avoid phenacetin altogether.


Phenacetin powder cas 62-44-2, once recognized for its pain-relieving properties, has faced regulatory limitations due to safety concerns. While it may have provided temporary relief in the past, the potential risks associated with prolonged or excessive use necessitate caution and informed decision-making. It is advisable to consult with healthcare professionals for alternative, safer pain management options.


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